One gammaretrovirus, Xenotropic murine leukemia virus-related virus ( XMRV ), is a recombinant virus created in a laboratory accident in the mid-1990s.
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The two major classes are recombinant viruses ( sometimes called biological nanoparticles or viral vectors ) and naked DNA or DNA complexes ( non-viral methods ).
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The new virus, according to the Australian team, was a natural version of the kind of recombinant viruses that can be crafted in a modern gene-splicing lab.
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When a cell is mixedly infected by two genetically marked viruses, recombinant virus progeny are often observed indicating that mating interaction had occurred at the DNA level.
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An example of a recombinant virus is Western equine encephalitis virus ( WEE ), which is a recombinant virus between two other closely related yet distinct encephalitis viruses.
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An example of a recombinant virus is Western equine encephalitis virus ( WEE ), which is a recombinant virus between two other closely related yet distinct encephalitis viruses.
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Antigens encoded by cancer-germline genes such as " MAGEA1 " and " MAGEA3 " have been used in the form of antigenic peptide, protein or recombinant viruses harbouring a sequence coding for the antigen.
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This has been demonstrated by coating biodegradable cationic microparticles ( such as poly ( lactide-co-glycolide ) formulated with cetyltrimethylammonium bromide ) with DNA . Such DNA-coated microparticles can be as effective at raising CTL as recombinant viruses, especially when mixed with alum.
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Techniques in development include : infecting tumors with recombinant viruses that make cancer cells vulnerable to antiviral and antibiotic agents; designing antibodies that attack cancers; and taking tumor cells out of the body, genetically altering them, and injecting them back into the body as vaccines that stimulate the immune system.
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"As mentioned above, recovery can be induced after virus infection, indicating that viruses can trigger PTGS . The induction of PTGS by viruses was confirmed by the observation that endogenous genes or transgenes can be silenced after infection with recombinant viruses carrying part of the ( trans ) gene sequence.
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